Physical Sciences › Chimie › Chimie organique › Synthesis and pharmacology of benzodiazepine derivatives

Synthesis and pharmacology of benzodiazepine derivatives

This cluster of papers focuses on the chemistry, synthesis, and biological evaluation of pyrrolobenzodiazepines, a class of DNA-interactive agents with potent antitumour activity. The research covers topics such as asymmetric synthesis, cross-linking agents, cytotoxicity, and their application in natural product synthesis.

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